Using the PreSonus HP60 headphone amplifier/mixer is easy. First, connect the correct power supply to ensure it works properly. Then, you can connect your audio source to the amplifier. Adjust the volume and mixing levels according to your preference. When not in use, turn off the device to save power. To maintain it, keep it in a dry and clean place. Avoid exposing it to extreme temperatures or moisture. If you notice any problems, stop using it immediately and contact customer service.