To use the Sennheiser SKM 500 G4 - AW wireless handheld transmitter, first ensure it's within the 470 - 558 MHz frequency range allowed in your country. Then, turn it on and pair it with your receiver. Hold the transmitter at a comfortable angle for clear sound pickup. Remember, always check your local wireless frequency laws before using it. For maintenance, keep it clean by using a soft, dry cloth. Avoid exposing it to extreme temperatures or moisture. If you face any issues, refer to the user manual or contact Sennheiser support.